CPP

CPP


Conventionally macromolecules such as proteins, nucleic acids and therapeutic macromolecules cannot cross the cell membrane spontaneously. Small protein domains, known as Cell Penetration Peptides (CPP) have been developed for the delivery of therapeutic macromolecules inside the eukaryotic cells, which enables administration of drugs through dermal, ocular and nasal routes. In addition, some CPPs have ability to carry cargoes into the brain crossing the BBB (blood brain Barrier). Even in the early stages of its development, CPPs have enabled the new DDS (Drug Delivery System) in many disease conditions.

Cell Penetrating Motif


A peptide sequences consisting of 7-30 amino acids that can effectively deliver biomolecules such as proteins and nucleic acids into the cytoplasm or nucleus of the cell, and used as a drug delivery system for the development of new drugs against various diseases such as cancer.

CPP

Normally living cells are not permeable to macromolecules such as, proteins and nucleic acids. Many of the drugs however need to be delivered inside the cytosol with effective amounts. Small protein domains, known as Cell Penetration Peptides (CPP) have been developed for delivery of therapeutic macromolecules inside the eukaryotic cells by administrating through dermal, ocular and nasal routes. The CPP have ability to carry cargos bypassing BBB (blood brain Barrier). Though in the early stages of its, CPP have enabled the new DDS (Drug Delivery System) in many disease conditions.
cpp1

Cell Penetrating Motif

A carrier that can effectively deliver biomolecules such as proteins and genes to the cytoplasm or nucleus by using a peptide consing of 7-30 amino acids.
Mainly applied as a drug delivery system for the development of various disease such as anticancer drugs.

AI-Applied TS-DDS Platform